Particle engineering for inhalation


Kuecept has developed 2 particle engineering technologies that enables the precise control over key particle characteristics that govern the performance of both DPI and pMDI formulations. 

These techniques allow us to achieve:

  • Optimal aerodynamic particle size (mass medium aerodynamic diameter)
  • Right aerodynamic diameter - function of density and dynamic shape factor
  • Narrow /and monodisperse particle size distribution
  • Low aerodynamic dispersion forces to aerosolise
  • Superior physical and chemical stability - high crystallinity, physicla form, low amorphous content etc. 

Technologies:

  • Combisphere™: Particle engineering for inhalation combination therapy (more)
  • Micron-Ease™: Production of custom made particles with good control of particle size distribution with improved processing efficiency. Ideal for molecules that are sensitive to traditional milling techniques