Solid-state characterisation of pharmaceuticals publication


As recognised experts in the field of pharmaceutical preformulation, Kuecept were pleased to be invited to contribute 2 chapters to the recently published "Solid State Characterization of Pharmaceuticals" book edited by Drs Richard Storey and Ingar Ymen.

In the book, Dr Mark Saunders discusses various practical aspects of thermal analytical techniques to characterise Active Pharmaceutical Ingredients, including DSC, TGA and DMA, whilst Dr Simon Gaisford discusses the use of isothermal solution microcalorimetry for characterising polymorphic purity and amorphous content. 

About the book: 

The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties.

This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included:

  1. Physical properties and processes
  2. Thermodynamics
  3. Intellectual guidance
  4. X-ray diffraction
  5. Spectroscopy Microscopy
  6. Particle sizing
  7. Mechanical properties
  8. Vapour sorption
  9. Thermal analysis & Calorimetry
  10. Polymorph prediction
  11. Form selection

For more information or to order your copy, please click here

 

16 November 2011